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The Capricornia Centre for Mucosal Immunology (CCMI) investigates complex host-pathogen interactions, immunity to infections in the respiratory tract and middle ear, to understand better disease processes and to facilitate the advancement of more effective therapies, including the development of vaccines.
In particular, our work focuses on characterising cell-mediated immunity to bacterial infection, appropriate regulation of which may promote protective rather than pathological responses, thereby leading to reduced signs and symptoms of disease. This rationale underpins the design of effective vaccine strategies.

A = Viral/Bacterial infection
B = Congestion/blockage of Eustachian tube
C = Mucus accumulation
D = Swelling/perforation of tympanic membrane
Middle ear infection and inflammation, otitis media, is one of the most common paediatric conditions with over 70% of children suffering from it in the first few years of life.
Australian Indigenous children have one of the highest incident rates in the world, with many becoming chronic sufferers resulting in persistent effusions, ruptured ear drums and hearing loss at a crucial stage in their development.
Hence, otitis media has a significant impact on the health, social and educational wellbeing of affected children and is of particular importance to rural communities in regional Queensland.

The Centre undertakes fundamental research as well as research consultancy services. It was founded in 2006 by Prof Jennelle Kyd and is currently directed by Prof Andrew Taylor-Robinson.
CCMI is an affiliated Centre of the Institute for Health and Social Science Research (IHSSR).